Understanding Diclofenac and Its Uses

Dosing

Dosage information for diclofenac varies depending on the condition being treated. For osteoarthritis, doses may range from 35 mg orally three times a day for diclofenac free acid capsules, to 100 mg orally once a day for diclofenac sodium extended-release tablets. The maximum daily dose is set at 150 mg.

For ankylosing spondylitis, diclofenac sodium enteric-coated and delayed-release tablets are typically taken at a dosage of 25 mg orally four times a day, with an additional 25 mg dose potentially administered at bedtime if necessary. The maximum daily dose for ankylosing spondylitis is 125 mg.

To address dysmenorrhea, diclofenac potassium immediate-release tablets are usually taken at a dosage of 50 mg orally three times a day. An initial dose of 100 mg orally, followed by 50 mg doses, may be more effective for some patients. Treatment should commence at the onset of symptoms and continue for a few days.

For rheumatoid arthritis, doses range from 50 mg orally three or four times a day for diclofenac potassium immediate-release tablets, to 100 mg orally once a day for diclofenac sodium extended-release tablets. In rare cases where the benefits outweigh the risks, a maximum daily dose of 100 mgof diclofenac sodium enteric-coated and delayed-release tablets may be prescribed.

It is crucial to adhere to the prescribed dosage and not exceed the recommended amount. If a dose is missed, it should be taken as soon as remembered. However, if it is almost time for the next scheduled dose, the missed dose should be skipped. Double doses should not be taken to make up for a missed one.

Drug interactions

Diclofenac may interact with other medications, including but not limited to aspirin, anticoagulants, corticosteroids, selective serotonin reuptake inhibitors (SSRIs), diuretics, and lithium. It is important to inform the doctor about all current medications, including over-the-counter drugs and herbal supplements, to avoid potential interactions.